Name
Bioprinting of Organ Models for Infection Studies
Description

Bioprinted organ model hold great potential to provide new tools for biomedical research. They combine two advantages over traditional approaches: In addition to contributing to the animal welfare efforts, humanized organ models can be generated that produce results high relevance for human (patho-)physiology. This feature contrasts animal experiments that are not always transferable to humans due to species-specific differences. These come particularly obvious in infection experiments as many human-pathogenic viruses do not infect test animals and adapted virus strains produce courses of infection that are irrelevant to humans. We have therefore developed bioprinted lung and liver models that we employ to study virus infection and to characterize the inhibitory potential of antiviral compounds. Our current studies also aim at providing a bioprinted, humanized lung model to study coronavirus infection and options to prevent virus spread. Throughout our bioprinting experiments, we aim at replacing materials of animal origin that are widely used in bioprinting, including fetal calf serum, Matrigel and gelatin. We suggest denoting bioprinting strategies free of any animal material as Clean Bioprinting.

Track
3D Bioprinting & Biomaterials
Time
8:00 AM - 8:45 AM
Timezone
EST
Session Type
Keynote
Virtual Session Link